BetaGlue® THERAPEUTICS

Targeted nuclear therapies

for solid tumours
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A new approach to pancreatic cancer therapy

YntraDose brings radiotherapy directly and only to the tumor

BetaGlue Therapeutics is pioneering targeted nuclear therapies for solid tumours. By combining biotechnology, nuclear science, and interventional oncology, we are advancing precision radiotherapeutics that deliver radiation directly where it matters most — inside the tumour. YntraDose, our solution, is designed to transform pancreatic cancer treatment through localized, effective, and safe therapy.

BetaGlueTherapeutics™ introduces YntraDose® – an innovative Yttrium-90 microsphere radiotherapy solution for the targeted and personalised treatment of solid tumours

By offering a novel easy-to-use interventional oncology treatment option YntraDose is set to become the new standard of care for a wide range of solid tumour cancer patient groups where current approaches fall short.

Innovation

Technology

The YntraDose radiotherapy platform is set to enable an entirely new treatment option for the benefit of patients and healthcare professionals alike.

BetaGlue yrridium

Evidence

Clinical Data

YntraDose has demonstrated preliminary safety and effectiveness in clinical use. Hear what the clinicians have to say about the potential of our technology.

PDAC

Pancreatic cancer demands a different approach

HCC

Hepatocellular Carcinoma

DCIS

Ductal Carcinoma In Situ

Process

Clinical workflow

4 steps to unfold YntraDose ®

1

Localize

Locate lesion or tumour injection site.

2

Prepare

YntraDose-90 added to the YntraDose-Glue syringe.

3

Treat

Attached YntraDose-Deliver injection system to YntraDose Syringe.

4

Assess the outcome

Assess focalized signal of implantation of YntraDose into injection site.

Leadership

Our team

Meet BetaGlue’s leadership team, main board and clinical advisory board.

Alexis Peyroles
Chief Executive Officer (CEO)

Alexis Peyroles

+ 25y Biotech and Pharma experience
Chairman Inside Tx & OWL Life Sciences

Salvatore Calabrese
Chief Financial Officer (CFO)

Salvatore Calabrese

+20 years of experience in the life sciences sector
Former CFO at Gain Therapeutics Inc.

Pietro Bubba Bello
Head of Manufacturing & Operations

Pietro Bubba Bello

Former Site Head, Director of Operations, and Plant Director of Operations and HSE Country Manager

Dr. Gianluca De Danieli
MD, MSc - Head of Clinical Development

Dr. Gianluca De Danieli

Former Medical Head, Italy and CEE at Advanced Accelerator Applications

Gaia Bisaccioni
Head of RA/QA

Gaia Bisaccioni

Former Quality Site Head at Advanced Accelerator Applications

Dr. Pieter Janssen
Head of Product Development

Dr. Pieter Janssen

20 years MedTech and Pharmaceutical R&D expertise at Johnson & Johnson, AstraZeneca,

Carol Hegarty
Head of Clinical Operations

Dr. Carol Hegarty

Over 20 years of experience in Clinical Operations within the medical device sector.

Process

Why we’re here

Today, radiotherapy treatment options have varying impact. Stereotactic Body Radiotherapy (SBRT) and Proton Beam Radiotherapy (PBRT), face challenges associated with internal organ movement and patient throughput. They also require substantial investment in specialised equipment and infrastructure, making them less accessible.

YntraDose represents a ground-breaking solution by circumventing these limitations.

It presents a potential new standard of care that aims to enhance treatment efficacy, reduce side effects, and make personalised cancer treatment more accessible to patients worldwide.

The impact of the clinical benefits for patients thanks to this new personalised radiotherapeutic treatment option are potentially broad.

Prof. Jafar Golzarian
Prof. Jafar Golzarian
Clinical advisor, oncology

Updates

Latest from BetaGlue

Clinical progress and company news from the field

BetaGlue Therapeutics Receives Belgium Ministry of Health Approval
BetaGlue Therapeutics Belgium Ministry of Health PDAC Cnlinical trial

BetaGlue Therapeutics Receives Belgium Ministry of Health Approval

BetaGlue Therapeutics Receives Belgium Ministry of Health Approval for YntraDose® Clinical Trial in Unresectable Locally Advanced Pancreatic Cancer (uLA-PDAC) Milan, December 15th, 2025 (GlobeNewswire) – BetaGlue® Therapeutics (“BetaGlue” or the…

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1200 800 Betaglue® Therapeutics
BetaGlue Therapeutics expands Clinical Trial in Italy to conduct its clinical study in unresectable locally advanced pancreatic cancer (uLA-PDAC)

BetaGlue Therapeutics expands Clinical Trial in Italy to conduct its clinical study in unresectable locally advanced pancreatic cancer (uLA-PDAC)

Milan, December 1st, 2025 (GlobeNewsire) BetaGlue Therapeutics Expands its Clinical Trial in Italy after obtaining approval from the Italian Ministry of Health to conduct clinical study in Unresectable Locally Advanced…

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1200 800 Betaglue® Therapeutics
MHRA Approves BetaGlue Therapeutics’ Clinical Trial Application for YntraDose™ in unresectable Locally Advanced Pancreatic Cancer (uLA-PDAC)

MHRA Approves BetaGlue Therapeutics’ Clinical Trial Application for YntraDose™ in unresectable Locally Advanced Pancreatic Cancer (uLA-PDAC)

Milan, November 12, 2025 (GlobeNewsire) – BetaGlue® Therapeutics (“BetaGlue” or the “Company”) a clinical-stage oncology company developing an innovative radiotherapy solution for the targeted treatment of solid tumours, announced today…

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