Precision

Nuclear medicine reimagined

Pioneering targeted nuclear therapies for solid tumors
Advancing precision oncology through innovative radiotherapeutics — starting with pancreatic cancer.

Origins

Our story

BetaGlue is an Italian biotech company developing next-generation nuclear therapies for solid tumors.

Born at the crossroads of biotechnology, radiochemistry, and interventional oncology, BetaGlue was founded with a single purpose: to turn nuclear science into targeted, effective treatments for cancers with limited therapeutic options.

From our headquarters in Italy, we collaborate with clinicians, scientists, and partners across Europe and the U.S. to bring innovative radiotherapeutics closer to patients who need them most.

Hybrid operating room at Policlinico Gemelli, Rome
YntraDose-90 vial in its lead shielding pot

Knowledge

Our science

Targeted nuclear medicine, redefined.

BetaGlue’s platform delivers radiation precisely where it matters most — inside the tumor.

Our lead program, YntraDose, enables interventional oncologists to deposit a therapeutic payload of beta-emitting isotopes directly within the tumor mass. This localized delivery aims to maximize tumor control while minimizing systemic exposure, making it a promising solution for pancreatic cancer and other hard-to-treat solid tumors.

Culture

Our values

We are opening new frontiers in precision oncology.
Pioneering earlier, effective treatments for any patient in an accessible and impactful way.

Because every cancer patient
deserves the best possible chance.

Method

Our approach

Scientific
excellence

Driven by rigorous clinical research, advanced materials science, and strong collaborations with leading academic centers.

Translational
innovation

Bridging nuclear physics, radiochemistry, and medical devices into a single, integrated therapeutic solution.

Real-world
focus

Designing every therapy to fit seamlessly into current clinical practice, enabling fast adoption and measurable patient benefit.

Our partnerships

Collaborating to accelerate innovation

BetaGlue partners with pharmaceutical companies, interventional radiology networks, and academic hospitals to advance clinical research, co-develop combination therapies, and scale manufacturing capabilities. Together, we aim to build the next generation of targeted radiotherapeutics that integrate seamlessly into modern cancer care.

Our hospitals

Great research centers

Our on-going early feasibility study in locally advanced pancreatic cancer is taking place in the following hospitals.

Future

Our vision

Our ambition is to make durable local tumor control a standard component of future precision oncology — an approach designed to complement next-generation systemic therapy rather than replace it.

Interventional radiologist and oncologist discussing a YntraDose treatment in front of a CT scan